APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000-1:2000 |
1:100-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 0.5% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
synthetic peptide derived from Beclin-1 at 110-190 aa.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ATG6,BECN1,VPS30,beclin 1,beclin1,Beclin-1
Cellular Localization
Cytoplasm,Golgi apparatus,Trans-Golgi network membrane,Endosome membrane,Endoplasmic reticulum membrane,Mitochondrion membrane,Endosome,Cytoplasmic vesicle,Autophagosome,Mitochondrion,Nucleus
Background
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Database
Research Area
DATA IMAGES
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GTX34055 IHC-P Image
IHC-P analysis of human brain tissue using GTX34055 Beclin 1 antibody [5C2]. Dilution : 1:200
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GTX34055 WB Image
WB analysis of (1) 293T cell lysate, (2) C2C12 cell lysate, (3) rat brain tissue lysates using GTX34055 Beclin 1 antibody [5C2]. Dilution : 1:2000
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GTX34055 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX34055 Beclin 1 antibody [5C2]. Dilution : 1:200
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REFERENCE
There are currently no references for Beclin 1 antibody [5C2] (GTX34055). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Beclin 1 antibody [5C2] (GTX34055). Be the first to share your experience with this product.