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Bestrophin 1 antibody

Anti-Bestrophin 1 antibody used in Western Blot (WB). GTX64583
Anti-Bestrophin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64583
Anti-Bestrophin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64583
Anti-Bestrophin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64583

Cat No. GTX64583

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human BEST1 (NP_004174.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

bestrophin 1 , ARB , BEST , BMD , Best1V1Delta2 , RP50 , TU15B , VMD2

Cellular Localization

Cell membrane

Background

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]

Database

Research Area

DATA IMAGES

Anti-Bestrophin 1 antibody used in Western Blot (WB). GTX64583

GTX64583 WB Image

WB analysis of various sample lysates using GTX64583 Bestrophin 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Bestrophin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64583

GTX64583 IHC-P Image

IHC-P analysis of human liver damage tissue using GTX64583 Bestrophin 1 antibody.
Dilution : 1:100

Anti-Bestrophin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64583

GTX64583 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64583 Bestrophin 1 antibody.
Dilution : 1:100

Anti-Bestrophin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64583

GTX64583 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64583 Bestrophin 1 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for Bestrophin 1 antibody (GTX64583). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339