GeneTex
United States (US)

Bestrophin 1 antibody

GTX64583_20180530_IHC-P_1_18121411_724.jpg
GTX64583_20180530_WB_18121411_163.jpg
GTX64583_20180530_IHC-P_18121411_120.jpg
GTX64583_20180530_IHC-P_2_18121411_986.jpg

Cat No. GTX64583

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

68 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human BEST1 (NP_004174.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

BEST1 Antibody , RP50 Antibody , ARB Antibody , BEST Antibody , TU15B Antibody , VMD2 Antibody , BMD Antibody

Background

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]

Database

DATA IMAGES
GTX64583_20180530_IHC-P_1_18121411_724.jpg

GTX64583 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64583 Bestrophin 1 antibody.
Dilution : 1:100

GTX64583_20180530_WB_18121411_163.jpg

GTX64583 WB Image

WB analysis of various samples using GTX64583 Bestrophin 1 antibody.The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

GTX64583_20180530_IHC-P_18121411_120.jpg

GTX64583 IHC-P Image

IHC-P analysis of human liver injury tissue using GTX64583 Bestrophin 1 antibody.
Dilution : 1:100

GTX64583_20180530_IHC-P_2_18121411_986.jpg

GTX64583 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64583 Bestrophin 1 antibody.
Dilution : 1:100

Package List Price ($)
$ 319