*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
This antibody detects the LAP*, LAP and LIP isoforms of C/EBP beta.
PBS, 1mg/ml BSA, 0.05% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Recombinant mouse LIP.
Protein G purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Ccaat/Enhancer Binding Protein (C/Ebp), Beta,C/Ebpbeta,Crp2,Il-6Dbp,Lap,Lip,Nf-Il6,Nf-M,Nfil6,Cebpb
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues.? These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP.? One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells.? Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation.? From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.