APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100-1:10000 |
Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Chimpanzee(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No Preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide corresponding to human c-peptide.
Purification
Affinity purified by Protein A.
Conjugation
Unconjugated
RRID
AB_2909984
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Cellular Localization
Secreted
Background
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Database
Research Area
DATA IMAGES
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GTX636462 IHC-P Image
C-Peptide antibody [HL1158] detects secreted C-Peptide protein by immunohistochemical analysis.Sample: Paraffin-embedded mouse pancreas.C-Peptide stained by C-Peptide antibody [HL1158] (GTX636462) diluted at 1:10000.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX636462 IHC-P Image
C-Peptide antibody [HL1158] detects secreted C-Peptide protein by immunohistochemical analysis.Sample: Paraffin-embedded human pancreas.C-Peptide stained by C-Peptide antibody [HL1158] (GTX636462) diluted at 1:10000.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX636462 IHC-P Image
C-Peptide antibody [HL1158] detects secreted C-Peptide protein by immunohistochemical analysis.Sample: Paraffin-embedded rat pancreas.C-Peptide stained by C-Peptide antibody [HL1158] (GTX636462) diluted at 1:10000.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX636462 ELISA Image
Indirect ELISA analysis performed by coating plate with recombinant mature C-Peptide protein (19.05-0.3 nM). Coated protein was probed with C-Peptide antibody [HL1158] (GTX636462) (1 μg/mL). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect bound primary antibody.
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REFERENCE
There are currently no references for C-Peptide antibody [HL1158] (GTX636462). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for C-Peptide antibody [HL1158] (GTX636462). Be the first to share your experience with this product.