*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
This antibody reacts with human C3c complement and with the C3c part of C3 and C3b.
PBS with <0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.
Batch dependent (Please refer to the vial label for the specific concentration.)
C3c Complement isolated from complement-activated human serum.
Fluorescein isothiocyanate (FITC)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
AHUS5 , ARMD9 , ASP , C3 , C3a , C3b , CPAMD1 , HELS62p , complement C3 , Complement C3
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]