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C3c antibody (FITC)

Cat No. GTX73472

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF

Reactivity

Human, Mouse, Rat, Goat, Sheep, Bovine, Cat, Dog, Guinea pig, Pig, Mink
Package
1 ml ($449)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

187 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts with human C3c complement and with the C3c part of C3 and C3b.

PROPERTIES

Form

Liquid

Buffer

PBS with <0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

C3c Complement isolated from complement-activated human serum.

Purification

Purified IgG

Conjugation

Fluorescein isothiocyanate (FITC)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AHUS5 , ARMD9 , ASP , C3 , C3a , C3b , CPAMD1 , HELS62p , complement C3 , Complement C3

Cellular Localization

Secreted

Background

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]

Database

Research Area

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 449