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C4 binding protein B antibody, N-term

Anti-C4 binding protein B antibody, N-term used in Western Blot (WB). GTX47750
Anti-C4 binding protein B antibody, N-term used in Western Blot (WB). GTX47750
Anti-C4 binding protein B antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47750

Cat No. GTX47750

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
50 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

Positive Control

human B lymphoblast , human fetal liver

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human C4 binding protein B.

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

complement component 4 binding protein beta , C4BP

Cellular Localization

Secreted

Background

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-C4 binding protein B antibody, N-term used in Western Blot (WB). GTX47750

GTX47750 WB Image

WB analysis of human fetal liver tissue using GTX47750 C4BPB antibody at 0.2-1μg/ml.

Anti-C4 binding protein B antibody, N-term used in Western Blot (WB). GTX47750

GTX47750 WB Image

WB analysis of human B lymphoblast cells using GTX47750 C4BPB antibody at 1μg/ml.

Anti-C4 binding protein B antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47750

GTX47750 IHC-P Image

IHC-P analysis of human kidney tissue using GTX47750 C4BPB antibody at 4.0-8.0μg/ml.

REFERENCE

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329