C4C antibody [99-72-18]

Cat. No. GTX49368

Host	Mouse
Clonality	Monoclonal
Clone Name	99-72-18
Isotype	IgG2b
Application	WB, ICC/IF, IP, ELISA, IHC
Reactivity	Human
Package	100 μl ($569)

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Datasheet
Document

View product citations for antibody GTX49368 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IP	Assay dependent
ELISA	Assay dependent
IHC	Assay dependent

Not tested in other applications.

Product Note

This antibody binds human complement factor C4c.

PROPERTIES

Form

Liquid

Buffer

0.01M Phosphate buffer, 0.5M NaCl

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR).

Purification

Protein-A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble). C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa). C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway.

Research Area

DATA IMAGES

GTX49368 IHC Image

IHC staining of human kidney with GTX49368. Strong staining of veins of nephritis kidney. Dilution: 1:600.

GTX49368 ICC/IF Image

IF staining of human kidney with GTX49368. Strong staining of veins of nephritis kidney. Dilution: 1:200.

GTX49368 IHC Image

IHC staining in human tonsil with GTX49368. Plasma in lumen of veins is stained strongly as well as follicular dendritic cells in germinal center of tonsil. Dilution: 1:600.

GTX49368 ICC/IF Image

IF staining in human tonsil with GTX49368. Plasma in lumen of veins is stained strongly in tonsil tissue. Dilution: 1:200.

GTX49368 IHC Image

IHC staining of human liver with GTX49368. Cytoplasm of hepatocytes labelled moderately and plasma of veins strongly in liver tissue. Dilution: 1:600.

GTX49368 ELISA Image

The calibration curve of a sandwich assay for Anti-Factor XII using GTX49368 as the capture antibody and GTX60995-02 as the biotinylated detection antibody.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 569

Qty

C4C antibody [99-72-18]

Cat. No. GTX49368

Host

Clonality

Clone Name

Isotype

Application

Reactivity

APPLICATION

Application Note

Product Note

PROPERTIES

Form

Buffer

Preservative

Storage

Concentration

Immunogen

Purification

Conjugation

Note

TARGET

Background

Research Area

DATA IMAGES

GTX49368 IHC Image

GTX49368 ICC/IF Image

GTX49368 IHC Image

GTX49368 ICC/IF Image

GTX49368 IHC Image

GTX49368 ELISA Image

REFERENCE

REVIEW

Product

Research

Support

Company

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All products are for research use only—Not for use in diagnostic or therapeutic applications.