GeneTex

  • Country / Location Selection

United States (US)

C4d antibody [057-51.5.1.6]

Cat. No. GTX42599

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 057-51.5.1.6

Isotype

 IgG1

Application

 IHC-Fr, FACS, ELISA

Reactivity

 Human
Package
100 μg ($689)
See all C4d products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr Assay dependent
FACS Assay dependent
ELISA Assay dependent
Not tested in other applications.

Product Note

This antibody recognizes a neoantigen on the secreted protein complement component 4d (C4d).

PROPERTIES

Form

Liquid

Buffer

Borate buffered saline

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human C4d

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C4AD Antibody , CO4 Antibody , CPAMD2 Antibody , C4A6 Antibody , C4A3 Antibody , complement component 4A (Rodgers blood group) Antibody , C4A Antibody , C4 Antibody , C4S Antibody , RG Antibody , C4A4 Antibody , C4A2 Antibody

Background

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Research Area

REFERENCE

There are currently no references for C4d antibody [057-51.5.1.6] (GTX42599). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for C4d antibody [057-51.5.1.6] (GTX42599). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 689