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C5 antibody [215]

Anti-C5 antibody [215] used in IHC (Paraffin sections) (IHC-P). GTX02119

Cat No. GTX02119

Host

Rabbit

Clonality

Monoclonal

Clone Name

215

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:500
Not tested in other applications.

Calculated MW

188 kDa. ( Note )

Product Note

It has cross-reactivity with human A2M protein in ELISA assay.

PROPERTIES

Form

Liquid

Buffer

0.2μm-filtered PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human Complement C5a protein

Purification

Purified by Protein A

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

complement C5 , C5D , C5a , C5b , CPAMD4 , ECLZB

Cellular Localization

Secreted

Background

This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-C5 antibody [215] used in IHC (Paraffin sections) (IHC-P). GTX02119

GTX02119 IHC-P Image

IHC-P analysis of human cirrhosis tissue section using GTX02119 C5 antibody [215].
Dilution : 1:200

REFERENCE

There are currently no references for C5 antibody [215] (GTX02119). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for C5 antibody [215] (GTX02119). Be the first to share your experience with this product.
Package List Price ($)
$ 339