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C7 antibody, Internal

Anti-C7 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX80456
Anti-C7 antibody, Internal used in Western Blot (WB). GTX80456
Anti-C7 antibody, Internal used in Flow cytometry (FACS). GTX80456

Cat. No. GTX80456

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human
Package
400 μl ($399)
See all C7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 375-403 amino acids from the Central region of human C7.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement C7

Cellular Localization

Secreted

Background

This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016]

Database

Research Area

DATA IMAGES

Anti-C7 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX80456

GTX80456 IHC-P Image

IHC-P analysis of human lymph tissue using GTX80456 C7 antibody, Internal.

Anti-C7 antibody, Internal used in Western Blot (WB). GTX80456

GTX80456 WB Image

WB analysis of Ramos cell lysate (35ug/lane) using GTX80456 C7 antibody, Internal.

Anti-C7 antibody, Internal used in Flow cytometry (FACS). GTX80456

GTX80456 FACS Image

FACS analysis of Ramos cells using GTX80456 C7 antibody, Internal.
Top histogram : negative control
Bottom histogram : Ramos cells

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399