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C9 antibody [002-94.8.8]

Cat. No. GTX42591

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 002-94.8.8

Isotype

 IgG2b

Application

 ELISA

Reactivity

 Human
Package
100 μg ($579)
See all C9 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA Assay dependent
Not tested in other applications.

Calculated MW

63 kDa. ( Note )

Product Note

This antibody recognizes complement component 9 (C9) and does not recognise MAC.

PROPERTIES

Form

Liquid

Buffer

Borate buffered saline

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human C9

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement C9 , ARMD15 , C9D

Cellular Localization

Secreted

Background

This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]

Database

Research Area

REFERENCE

Application Reference

Dane TL et al. Front Cell Neurosci 2023; 17 : 1134090 Reduced C9orf72 expression exacerbates polyGR toxicity in patient iPSC-derived motor neurons and a Type I protein arginine methyltransferase inhibitor reduces that toxicity.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 579