*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Human Kidney Tissue Slide
This antibody is human specific. At least three isoforms are known to exist; this antibody will only detect isoform 1. This antibody is predicted not to cross-react with other CARMA proteins.
PBS with 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
CARD10 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CARD10.The immunogen is located within the first 50 amino acids of CARD10.
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Caspase Recruitment Domain Family Member 10,Bimp1,Carma3,Card10
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]