GeneTex
United States (US)

CARD14 antibody

Anti-CARD14 antibody used in IHC (Paraffin sections) (IHC-P). GTX31281

Cat No. GTX31281

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

113 kDa. ( Note )

Specificity/Sensitivity

CARMA2 antibody is human specific. At least three isoforms of CARMA2 are known to exist; this antibody will only detect isoform 1. CARMA2 antibody is predicted not to cross-react with other CARMA proteins.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CARD14 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human CARD14.The immunogen is located within the last 50 amino acids of CARD14.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Caspase Recruitment Domain Family Member 14,Bimp2,Carma2,Prp,Psors2,Pss1,Card14

Background

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]

Database

Research Area

DATA IMAGES
Anti-CARD14 antibody used in IHC (Paraffin sections) (IHC-P). GTX31281

GTX31281 IHC-P Image

IHC-P analysis of human placenta tissue using GTX31281 CARD14 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329