APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 μg/mL |
| 20 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Mouse Brain Tissue Lysate(GTX27934)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
CASK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CASK.The immunogen is located within amino acids 760 - 810 of CASK.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
calcium/calmodulin dependent serine protein kinase , CAGH39 , CAMGUK , CMG , FGS4 , LIN2 , MICPCH , MRXSNA , TNRC8 , hCASK
Cellular Localization
Nucleus,Cytoplasm,Cell membrane
Background
This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
Database
Research Area
DATA IMAGES
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GTX31858 WB Image
WB analysis of mouse brain tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX31858 CASK antibody.
Working concentration : 1 μg/ml
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GTX31858 IHC-P Image
IHC-P analysis of human brain tissue using GTX31858 CASK antibody.
Working concentration : 20 μg/ml
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REFERENCE
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REVIEW
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