CBL antibody [C2C3], C-term

Name: CBL antibody [C2C3], C-term
Brand: GeneTex
SKU: GTX101352
Price: 399.00 USD
Rating: 3 (1 reviews)

Anti-CBL antibody [C2C3], C-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX101352

Anti-CBL antibody [C2C3], C-term used in Western Blot (WB). GTX101352

Cat. No. GTX101352

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF
Reactivity	Human
Package	100 μl ($399), 25 μl ($169)

See all CBL products

Datasheet
Document

View product citations for antibody GTX101352 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000
ICC/IF	1:50-1:200

Not tested in other applications.

Calculated MW

100 kDa. ( Note )

Positive Control

THP-1

Predict Reactivity

Mouse, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 40% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human CBL. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2036459

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Cbl proto-oncogene , C-CBL , CBL2 , FRA11B , NSLL , RNF55

Cellular Localization

Cytoplasm

Background

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq]

Database

Gene ID: 867 CBL
UniProt: P22681 CBL

Research Area

DATA IMAGES

GTX101352 ICC/IF Image

Immunofluorescence analysis of methanol-fixed A431, using CBL(GTX101352) antibody at 1:50 dilution.

GTX101352 WB Image

CBL antibody [C2C3], C-term detects CBL protein by Western blot analysis.
A. 30 μg THP-1 whole cell lysate/extract
7.5 % SDS-PAGE
CBL antibody [C2C3], C-term (GTX101352) dilution: 1:1000

REFERENCE

There are currently no references for CBL antibody [C2C3], C-term (GTX101352). Be the first to share your publications with this product.

Submit a Reference

REVIEW