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CBS antibody

Anti-CBS antibody used in IHC (Paraffin sections) (IHC-P). GTX55551
Anti-CBS antibody used in Western Blot (WB). GTX55551
Anti-CBS antibody used in IHC (Paraffin sections) (IHC-P). GTX55551

Cat. No. GTX55551

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CBS products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 252-551 of human CBS (NP_000062.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cystathionine-beta-synthase , CBSL , HIP4

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-CBS antibody used in IHC (Paraffin sections) (IHC-P). GTX55551

GTX55551 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX55551 CBS antibody.
Blue : DAPI
Dilution : 1:100

Anti-CBS antibody used in Western Blot (WB). GTX55551

GTX55551 WB Image

WB analysis of various sample lysates using GTX55551 CBS antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-CBS antibody used in IHC (Paraffin sections) (IHC-P). GTX55551

GTX55551 IHC-P Image

IHC-P analysis of rat liver tissue using GTX55551 CBS antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399