*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Mouse, Zebrafish, Drosophila, Chicken, Xenopus(>80% identity)
Filter-sterilized 0.12 M sodium phosphate buffer (pH 7.4), 50% glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.44 mg/ml (Please refer to the vial label for the specific concentration.)
synthetic peptide CNEDDDKKDDKN including the C-terminal sequence (176-185) of human HP1beta
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
chromobox 1 , CBX , HP1-BETA , HP1Hs-beta , HP1Hsbeta , M31 , MOD1 , p25beta
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
GTX00736 ICC/IF Image
ICC/IF analysis of Baby Hamster Kidney cells using GTX00736 CBX1 / HP1 beta antibody.
Fixation : 4% PFA
GTX00736 WB Image
WB analysis of MCF-7 whole cell lysate using GTX00736 CBX1 / HP1 beta antibody.
Dilution : 1:1000