APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 5 μg/ml |
| Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Bovine, Gibbon, Gorilla, Marmoset(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 20 amino acid peptide from 2nd extracellular domain of human CCR1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375150
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine receptor 1 , CC motif chemokine receptor 1 , CCR1 , CD191 , CKR1 , CMKBR1 , HM145 , MIP1aR , SCYAR1
Cellular Localization
Cell membrane
Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
|
GTX70509 IHC-P Image
IHC-P analysis of human spleen, lymphocytes tissue using GTX70509 CCR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX70509 IHC-P Image
IHC-P analysis of brain amygdala neurons and glia tissue using GTX70509 CCR1 antibody.
|
|
|
GTX70509 IHC-P Image
IHC-P analysis of human colon, carcinoma tissue using GTX70509 CCR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX70509 IHC-P Image
IHC-P analysis of colon ulcerative colitis eosinophils tissue using GTX70509 CCR1 antibody.
|
|
|
GTX70509 IHC-P Image
IHC-P analysis of human lung, adenocarcinoma tissue using GTX70509 CCR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX70509 IHC-P Image
IHC-P analysis of human lung tissue using GTX70509 CCR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX70509 IHC-P Image
IHC-P analysis of pancreas, adenocarcinoma tissue using GTX70509 CCR1 antibody.
|
REFERENCE
REVIEW
There are currently no reviews for CCR1 antibody (GTX70509). Be the first to share your experience with this product.
