APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:1000 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Human, Rat, Sheep, Bovine, Pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 20% Glycerol
Preservative
0.025% ProClin 300
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1.03 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human CCR10. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_2886720
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
C-C motif chemokine receptor 10 , GPR2
Cellular Localization
Cell membrane; Multi-pass membrane protein
Background
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
Database
Research Area
DATA IMAGES
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GTX132707 IHC-P Image
CCR10 antibody detects CCR10 protein at cell membrane and cytoplasm by immunohistochemical analysis.Sample: Paraffin-embedded mouse lymph node.CCR10 stained by CCR10 antibody (GTX132707) diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX132707 IHC-P Image
CCR10 antibody detects CCR10 protein at cell membrane and cytoplasm by immunohistochemical analysis.Sample: Paraffin-embedded mouse thymus gland.CCR10 stained by CCR10 antibody (GTX132707) diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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REFERENCE
There are currently no references for CCR10 antibody (GTX132707). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CCR10 antibody (GTX132707). Be the first to share your experience with this product.
