CCR10 antibody

Cat. No. GTX23904

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, FACS, ELISA
Reactivity	Human, Mouse
Package	100 μg ($399)

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Datasheet

View product citations for antibody GTX23904 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500
IHC-P	1:125
FACS	1:12
ELISA	1:37,500

Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Product Note

Peptide sequence is < 50 % identical to other human chemokine receptors in this region.

PROPERTIES

Form

Liquid

Buffer

10mM KHPO₄, 140mM NaCl, 0.1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide VSWGHYSGDEEDAYSAEPLPELC corresponding to amino acids 9-31 of human CCR10

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CC motif chemokine receptor 10,CCR10,GPR2,C-C motif chemokine receptor 10

Cellular Localization

Cell membrane

Background

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

Database

Gene ID: 2826 CCR10
UniProt: P46092 CCR10

Research Area

DATA IMAGES

GTX23904 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX23904 CCR10 antibody.

REFERENCE

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REVIEW

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Package

List Price ($)

100 μg

$ 399

Qty