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CCR3 antibody [5E8] (APC)

Anti-CCR3 antibody [5E8] (APC) used in Flow cytometry (FACS). GTX00536-07

Cat. No. GTX00536-07

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5E8

Isotype

 IgG2b

Application

 FACS

Reactivity

 Human
Package
100 test ($359)
See all CCR3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Purified by size-exclusion chromatography

Conjugation

Allophycocyanin (APC)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CC motif chemokine receptor 3 , CCCKR3 , CCR3 , CD193 , CKR3 , CMKBR3 , C-C motif chemokine receptor 3

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-CCR3 antibody [5E8] (APC) used in Flow cytometry (FACS). GTX00536-07

GTX00536-07 FACS Image

FACS analysis of human peripheral blood using GTX00536-07 CCR3 antibody [500000000] (APC).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 359