APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
| 1:100-1:1000 |
Not tested in other applications.
Calculated MW
Positive Control
K562
Predict Reactivity
Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 20% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCR3. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_1240567
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine receptor 3 , CC-CKR-3 , CD193 , CKR3 , CMKBR3
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
Database
Research Area
DATA IMAGES
![Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342](/templates/default/js/lightbox/images/loading.gif "Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342")
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GTX100342 IHC-P Image
CCR3 antibody [C2C3], C-term detects CCR3 protein at cytosol on human ovarian carcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded human ovarian carcinoma.
CCR3 antibody [C2C3], C-term (GTX100342) dilution: 1:500.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
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GTX100342 WB Image
Sample (30 ug of whole cell lysate)
A: K562
10% SDS PAGE
GTX100342 diluted at 1:1000
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GTX100342 IHC-P Image
CCR3 antibody [C2C3], C-term detects CCR3 protein at cytosol on human colon carcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded human colon carcinoma.
CCR3 antibody [C2C3], C-term (GTX100342) dilution: 1:500.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
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REFERENCE
There are currently no references for CCR3 antibody [C2C3], C-term (GTX100342). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CCR3 antibody [C2C3], C-term (GTX100342). Be the first to share your experience with this product.
![Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342](/upload/website/prouct_img/small/GTX100342/GTX100342_39568_IHC_w_23060100_567.webp "Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342")
![Anti-CCR3 antibody [C2C3], C-term used in Western Blot (WB). GTX100342](/upload/website/prouct_img/small/GTX100342/GTX100342_39568_WB_w_23060100_735.webp "Anti-CCR3 antibody [C2C3], C-term used in Western Blot (WB). GTX100342")
![Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342](/upload/website/prouct_img/small/GTX100342/GTX100342_39568_IHC_2_w_23060100_196.webp "Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342")
![Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342](/upload/website/prouct_img/normal/GTX100342/GTX100342_39568_IHC_w_23060100_567.webp "Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342")
![Anti-CCR3 antibody [C2C3], C-term used in Western Blot (WB). GTX100342](/upload/website/prouct_img/normal/GTX100342/GTX100342_39568_WB_w_23060100_735.webp "Anti-CCR3 antibody [C2C3], C-term used in Western Blot (WB). GTX100342")
![Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342](/upload/website/prouct_img/normal/GTX100342/GTX100342_39568_IHC_2_w_23060100_196.webp "Anti-CCR3 antibody [C2C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100342")