GeneTex
United States (US)

CCR3 antibody

Anti-CCR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX31254
Anti-CCR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX31254
Anti-CCR3 antibody used in Western Blot (WB). GTX31254

Cat No. GTX31254

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

Human Spleen Tissue Lysate(GTX27921) , Human Spleen Tissue Slide

Specificity/Sensitivity

At least three isoforms of CCR3 are known to exist; this antibody will detect all three isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CCR3 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human CCR3.The immunogen is located within the last 50 amino acids of CCR3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-C Motif Chemokine Receptor 3,Cc-Ckr-3,Cd193,Ckr3,Cmkbr3,Ccr3

Background

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES
Anti-CCR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX31254

GTX31254 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31254 CCR3 antibody.
Working concentration : 20 μg/ml

Anti-CCR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX31254

GTX31254 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31254 CCR3 antibody.
Working concentration : 10 μg/ml

Anti-CCR3 antibody used in Western Blot (WB). GTX31254

GTX31254 WB Image

WB analysis of human spleen tissue lysates at different concentration(lane 1 and 2) or in the presence of blocking peptide (lane 3) using GTX31254 CCR3 antibody.
Working concentration : 1 μg/ml (lane 1), 2 μg/ml (lane 2), and 2 μg/ml(lane 3)

Package List Price ($)
$ 329