GeneTex
United States (US)

CCR3 antibody

GTX31255_2458_WB_20180221_18121410_131.jpg

Cat No. GTX31255

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

Human Spleen Tissue Lysate(GTX27921)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CCR3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CCR3.The immunogen is located within the first 50 amino acids of CCR3.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-C Motif Chemokine Receptor 3,Cc-Ckr-3,Cd193,Ckr3,Cmkbr3,Ccr3

Background

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES
GTX31255_2458_WB_20180221_18121410_131.jpg

GTX31255 WB Image

WB analysis of human spleen tissue lysates at different concentration(lane 1 and 2) or in the presence of blocking peptide (lane 3) using GTX31255 CCR3 antibody.
Working concentration : 1μg/ml (lane 1), 2 μg/ml (lane 2), and 2 μg/ml (lane 3)

Package List Price ($)
$ 329