APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 8 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rabbit, Bovine, Dog, Hamster, Gibbon, Gorilla, Horse, Marmoset(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human CCR3.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375314
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine receptor 3 , CC motif chemokine receptor 3 , CCCKR3 , CCR3 , CD193 , CKR3 , CMKBR3
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Database
Research Area
DATA IMAGES
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GTX70771 IHC-P Image
IHC-P analysis of human nasal mucosa, allergic rhinitis tissue using GTX70771 CCR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX70771 IHC-P Image
IHC-P analysis of brain, alzheimer's disease, senile plaque tissue using GTX70771 CCR3 antibody.
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GTX70771 IHC-P Image
IHC-P analysis of human prostate, carcinoma tissue using GTX70771 CCR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX70771 IHC-P Image
IHC-P analysis of tonsil, immunoblasts tissue using GTX70771 CCR3 antibody.
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GTX70771 IHC-P Image
IHC-P analysis of human tonsil tissue using GTX70771 CCR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
There are currently no references for CCR3 antibody (GTX70771). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CCR3 antibody (GTX70771). Be the first to share your experience with this product.
