Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 |
Assay dependent |
Assay dependent |
1:12 |
1:30,000 |
1:200 |
Not tested in other applications.
Calculated MW
Product Note
Peptide sequence is < 50 % identical to other human chemokine receptors in this region.
Form
Liquid
Buffer
10mM KHPO₄, 140mM NaCl, 0.1% BSA
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
17SNYYLYESIPKPCTKEGIKAFGE39 corresponding to human CCR4 extracellular domain
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
CC motif chemokine receptor 4,CCCKR4,CCR4,CD194,CKR4,CMKBR4,ChemR13,HGCN:14099,K55,C-C motif chemokine receptor 4
Cellular Localization
Cell membrane
Background
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]
Database
Research Area