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CCR5 antibody [HEK/1/85a] (PE)

Anti-CCR5 antibody [HEK/1/85a] (PE) used in Flow cytometry (FACS). GTX75915

Cat No. GTX75915

Host

Rat

Clonality

Monoclonal

Clone Name

HEK/1/85a

Isotype

IgG2a

Application

FACS

Reactivity

Human
Package
1 ml ($409)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Neat - 1/5

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Not tested in other applications.

Calculated MW

41 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CHO cells transfected with human CCR5.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

C-C Motif Chemokine Receptor 5 (Gene/Pseudogene) , Cc-Ckr-5 , Ccckr5 , Ccr-5 , Cd195 , Ckr-5 , Ckr5 , Cmkbr5 , Iddm22 , Ccr5

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CCR5 antibody [HEK/1/85a] (PE) used in Flow cytometry (FACS). GTX75915

GTX75915 FACS Image

Image A. Alexa Fluor 488 conjugated Mouse anti Human CD3 and RPE conjugated Rat IgG2a isotype control. Image B. Alexa Fluor 488 conjugated Mouse anti Human CD3 and RPE conjugated Rat anti Human CCR5 (GTX75915). All experiments performed on human Peripheral blood lymphocytes

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf