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CCR5 antibody [HEK/1/85a]

Cat No. GTX75914

Host

Rat

Clonality

Monoclonal

Clone Name

HEK/1/85a

Isotype

IgG2a

Application

FACS

Reactivity

Human
Package
100 μg ($299)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 1/50-1/100

Note :

FACS
Use 10μl of the suggested working dilution to label 100μl fresh whole blood.

Not tested in other applications.

Calculated MW

41 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CHO cells transfected with human CCR5.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

C-C Motif Chemokine Receptor 5 (Gene/Pseudogene) , Cc-Ckr-5 , Ccckr5 , Ccr-5 , Cd195 , Ckr-5 , Ckr5 , Cmkbr5 , Iddm22 , Ccr5

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for CCR5 antibody [HEK/1/85a] (GTX75914). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CCR5 antibody [HEK/1/85a] (GTX75914). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf