APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1/250 |
| 1/125 |
| 1/35,000 |
|
Note :
WB
This antibody cross-reacts with mouse CD196, where linear epitopes areaccessible.
ELISA
This product is suitable for use in indirect ELISA applications.
|
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes human CCR6 (CD196). This antibody cross-reacts with mouse CCR6.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide YFVSVNTSYYSVDSEMLLCSLQEVRQFSR corresponding to amino acids 18-46 of human CCR6.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine receptor 6 , BN-1 , C-C CKR-6 , CC-CKR-6 , CCR-6 , CD196 , CKR-L3 , CKRL3 , CMKBR6 , DCR2 , DRY6 , GPR29 , GPRCY4 , STRL22
Cellular Localization
Cell membrane
Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX42317 IHC-P Image
IHC-P analysis of mouse spleen tissue using GTX42317 CCR6 antibody.
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GTX42317 IHC-P Image
IHC-P analysis of human spleen tissue using GTX42317 CCR6 antibody.
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REFERENCE
There are currently no references for CCR6 antibody (GTX42317). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CCR6 antibody (GTX42317). Be the first to share your experience with this product.
