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CCR7 antibody [9L11]

Cat No. GTX52518

Host

Mouse

Clonality

Monoclonal

Clone Name

9L11

Isotype

IgG2

Application

IHC-P, FACS

Reactivity

Human
Package
100 μg ($459)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50 - 1:200
FACS 1:100 - 1:800
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human CCR7 transfected 293 cells

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

BLR2 , CC motif chemokine receptor 7 , CCCKR7 , CCR7 , CD197 , CDw197 , CMKBR7 , EBI1 , C-C motif chemokine receptor 7

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Database

Research Area

REFERENCE

There are currently no references for CCR7 antibody [9L11] (GTX52518). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CCR7 antibody [9L11] (GTX52518). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 459