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CCR7 antibody

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953
Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953
Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953
Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953

Cat No. GTX12953

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 10 - 20 μg/ml
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Predict Reactivity

Rabbit, Bovine, Dog, Pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from 1st extracellular domain of human CCR7.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

C-C motif chemokine receptor 7 , BLR2 , CC motif chemokine receptor 7 , CCCKR7 , CCR7 , CD197 , CDw197 , CMKBR7 , EBI1

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Database

Research Area

DATA IMAGES

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953

GTX12953 IHC-P Image

IHC-P analysis of hodgkin's disease reed sternberg cells tissue using GTX12953 CCR7 antibody.

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953

GTX12953 IHC-P Image

IHC-P analysis of lymph node, eosinophilic granuloma langerhans histiocytes tissue using GTX12953 CCR7 antibody.

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953

GTX12953 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX12953 CCR7 antibody.

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX12953

GTX12953 IHC-P Image

IHC-P analysis of human lymph node tissue using GTX12953 CCR7 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

There are currently no reviews for CCR7 antibody (GTX12953). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 269