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CCR7 antibody

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX31906
Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX31906
Anti-CCR7 antibody used in Western Blot (WB). GTX31906

Cat No. GTX31906

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

Human Spleen Tissue Lysate(GTX27921) , Human Spleen Tissue Slide

Specificity/Sensitivity

CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7.The immunogen is located within amino acids 180 - 230 of CCR7.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

C-C motif chemokine receptor 7 , BLR2 , CC-CKR-7 , CCR-7 , CD197 , CDw197 , CMKBR7 , EBI1

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Database

Research Area

DATA IMAGES

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX31906

GTX31906 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31906 CCR7 antibody.
Working concentration : 5 μg/ml

Anti-CCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX31906

GTX31906 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31906 CCR7 antibody.
Working concentration : 20 μg/ml

Anti-CCR7 antibody used in Western Blot (WB). GTX31906

GTX31906 WB Image

WB analysis of human spleen tissue lysate using GTX31906 CCR7 antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339