APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Spleen Tissue Lysate(GTX27921) , Human Spleen Tissue Slide
Product Note
CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7.The immunogen is located within amino acids 180 - 230 of CCR7.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine receptor 7 , BLR2 , CC-CKR-7 , CCR-7 , CD197 , CDw197 , CMKBR7 , EBI1
Cellular Localization
Cell membrane; Multi-pass membrane protein
Background
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Database
Research Area
DATA IMAGES
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GTX31906 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31906 CCR7 antibody.
Working concentration : 5 μg/ml
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GTX31906 WB Image
WB analysis of human spleen tissue lysate using GTX31906 CCR7 antibody.
Working concentration : 1 μg/ml
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GTX31906 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31906 CCR7 antibody.
Working concentration : 20 μg/ml
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REFERENCE
There are currently no references for CCR7 antibody (GTX31906). Be the first to share your publications with this product.
REVIEW
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