GeneTex
  • Country / Location Selection

United States (US)

CD10 antibody [56C6]

Anti-CD10 antibody [56C6] used in IHC (Paraffin sections) (IHC-P). GTX75376

Cat No. GTX75376

Host

Mouse

Clonality

Monoclonal

Clone Name

56C6

Isotype

IgG1

Application

WB, IHC-P, IHC-Fr

Reactivity

Human, Cynomolgus monkey
Package
50 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/50-1/100
IHC-P 1/80
IHC-Fr 1/80

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

Not tested in other applications.

Calculated MW

86 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue Culture Supernatant with 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant human CD10.

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Membrane Metalloendopeptidase , Calla , Cd10 , Cmt2T , Nep , Sca43 , Sfe , Mme

Background

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD10 antibody [56C6] used in IHC (Paraffin sections) (IHC-P). GTX75376

GTX75376 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX75376 CD10 antibody [56C6].

REFERENCE

There are currently no references for CD10 antibody [56C6] (GTX75376). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD10 antibody [56C6] (GTX75376). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 169