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CD10 antibody [MEM-78] (Biotin)

Anti-CD10 antibody [MEM-78] (Biotin) used in Flow cytometry (FACS). GTX78262

Cat. No. GTX78262

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-78

Isotype

 IgG1

Application

 FACS, IP

Reactivity

 Human
Package
100 μg ($399)
See all CD10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

86 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NALM-6 human pre-B cell line

Purification

Purified IgG

Conjugation

Biotin
The reagent is free of unconjugated biotin.

RRID

AB_625677

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CALLA , CD10 , CMT2T , MME , NEP , SCA43 , SFE , membrane metalloendopeptidase , Neprilysin

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-CD10 antibody [MEM-78] (Biotin) used in Flow cytometry (FACS). GTX78262

GTX78262 FACS Image

Surface staining of NALM-6 human pre-B cell leukemia cell line with anti-human CD10: PE (GTX78264). Total viable cells were used for analysis.

REFERENCE

Clone Reference

Huang WY et al. Cancers (Basel) 2022; 14 (13) Cancer-Associated Fibroblasts Promote Tumor Aggressiveness in Head and Neck Cancer through Chemokine Ligand 11 and C-C Motif Chemokine Receptor 3 Signaling Circuit.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399