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CD10 antibody [MME/1892]

Anti-CD10 antibody [MME/1892] used in Protein Array (Protein Array). GTX18043
Anti-CD10 antibody [MME/1892] used in IHC (Paraffin sections) (IHC-P). GTX18043
Anti-CD10 antibody [MME/1892] used in Western Blot (WB). GTX18043
Anti-CD10 antibody [MME/1892] used in Western Blot (WB). GTX18043

Cat. No. GTX18043

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MME/1892

Isotype

 IgG2c

Application

 WB, IHC-P, ELISA, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all CD10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
ELISA 2-4μg/ml (for coating)
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

86 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human CD10 protein fragment (aa297-483) (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CALLA , CD10 , CMT2T , MME , NEP , SCA43 , SFE , membrane metalloendopeptidase , Neprilysin

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-CD10 antibody [MME/1892] used in Protein Array (Protein Array). GTX18043

GTX18043 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using CD10 Mouse Monoclonal Antibody (MME/1892). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-CD10 antibody [MME/1892] used in IHC (Paraffin sections) (IHC-P). GTX18043

GTX18043 IHC-P Image

IHC-P analysis of human kidney tissue using GTX18043 CD10 antibody [MME/1892].

Anti-CD10 antibody [MME/1892] used in Western Blot (WB). GTX18043

GTX18043 WB Image

WB analysis of (1) Raji and (2) Ramos cell lysates using GTX18043 CD10 antibody [MME/1892].

Anti-CD10 antibody [MME/1892] used in Western Blot (WB). GTX18043

GTX18043 WB Image

WB analysis of kidney tissue lysate using GTX18043 CD10 antibody [MME/1892].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529