*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Jurkat , mouse kidney , rat kidney
Rabbit, Bovine, Dog, Rhesus Monkey(>80% identity)
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.)
Recombinant protein encompassing a sequence within the center region of human CD10. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CALLA antibody, CD10 antibody, DKFZp686O16152 antibody, MGC126681 antibody, MGC126707 antibody, NEP antibody, SFE antibody, MME antibody, membrane metallo-endopeptidase variant 2 antibody, neprilysin antibody, atriopeptidase antibody, enkephalinase antibody, membrane metallo-endopeptidase variant 1 antibody, membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) antibody, skin fibroblast elastase antibody, neutral endopeptidase 24.11 antibody, membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody, common acute lymphocytic leukemia antigen antibody, membrane metallo-endopeptidase antibody
Cell membrane; Single-pass type II membrane protein
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq]