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CD105 antibody [1G2]

Cat. No. GTX19672

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1G2

Isotype

 IgG3

Application

 FACS

Reactivity

 Human
Package
100 μg ($339)
See all CD105 products

APPLICATION

Application Note

FACS: Use 2μg for 10^5 cells. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

71 kDa. ( Note )

Product Note

1G2 stains endothelial cells from various tissues and syncytiotrophoblasts. Stains intensely on high endothelial venules (HEV), but does not react with peripheral blood cells, this antibody recognizes specifically proerythroblasts from bone marrow.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

CML blast crisis cells.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endoglin , END , HHT1 , ORW1

Cellular Localization

Cell membrane

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 339