CD105 antibody [3A9]

Cat. No. GTX60452

Host	Mouse
Clonality	Monoclonal
Clone Name	3A9
Isotype	IgG1
Application	WB, ICC/IF, IHC-P, FACS, ELISA
Reactivity	Human
Package	100 μl ($419)

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Datasheet
Document

View product citations for antibody GTX60452 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1/500 - 1/2000
ICC/IF	1/200 - 1/1000
IHC-P	1/200 - 1/1000
FACS	1/200 - 1/400
ELISA	1/10000

Not tested in other applications.

Calculated MW

71 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human CD105 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endoglin , END , HHT1 , ORW1

Cellular Localization

Cell membrane

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Database

Gene ID: 2022 ENG
UniProt: P17813 ENG

Research Area

DATA IMAGES

GTX60452 ELISA Image

ELISA analysis of antigen using GTX60452 CD105 antibody [3A9].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

GTX60452 IHC-P Image

IHC-P analysis of kidney cancer tissue (left) and stomach cancer tissue (right) using GTX60452 CD105 antibody [3A9].

GTX60452 FACS Image

FACS analysis of HepG2 cells using GTX60452 CD105 antibody [3A9].
Green : CD105
Purple : negative control

GTX60452 WB Image

WB analysis of HEK293 (1) and CD105(AA: 331-567)-hIgGFc transfected HEK293 (2) cell lysate using GTX60452 CD105 antibody [3A9].

GTX60452 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX60452 CD105 antibody [3A9].
Green : CD105
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 419

Qty