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CD105 antibody [MEM-229] (PE)

Anti-CD105 antibody [MEM-229] (PE) used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79975

Cat No. GTX79975

Host

Mouse

Clonality

Monoclonal

Clone Name

MEM-229

Isotype

IgG2a

Application

ICC/IF, FACS

Reactivity

Human, Pig
Package
100 test ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
FACS 20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Product Note

We do not recommend use of this product for Dog,Horse.

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin (PE)

RRID

AB_11169481

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

END , ENG , HHT1 , ORW1 , endoglin , CD105

Cellular Localization

Cell membrane

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-CD105 antibody [MEM-229] (PE) used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79975

GTX79975 ICC/IF Image

Immunofluorescence staining of an infarcted porcine heart with anti-CD105 (MEM-229; green;GTX79974); cell nuclei stained with DAPI (blue).

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf