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CD105 antibody [MEM-229] (PerCP-Cy5.5)

Cat. No. GTX78404-11

Reference 5

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-229

Isotype

 IgG2a

Application

 FACS

Reactivity

 Human, Pig
Package
100 test ($409)
See all CD105 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Product Note

We do not recommend use of this product for Dog,Horse samples.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.

Purification

Purified by size-exclusion chromatography

Conjugation

Peridinin-chlorophyll proteins-Cyanine5.5 (PerCP-Cy5.5)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

TARGET

Synonyms

END , ENG , HHT1 , ORW1 , endoglin , CD105

Cellular Localization

Cell membrane

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Database

Research Area

REFERENCE

Clone Reference

Khatri M et al. J Cell Physiol 2017; (Epub) Therapeutic potential of porcine bronchoalveolar fluid-derived mesenchymal stromal cells in a pig model of LPS-induced ALI.
Khatri M et al. Stem Cell Res Ther 2015; 6:222 Porcine lung mesenchymal stromal cells possess differentiation and immunoregulatory properties.
Yang J et al. J Res Med Sci 2014; 19 (2):112-6 Adipose-derived stem cells from the breast.
Onate B et al. BMC Genomics 2013; 14:625 Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in stemcellness and increased commitment to an adipocyte-like phenotype.
Tan Y et al. Tissue Eng Part A 2010; 16 (1):67-79 Meniscus reconstruction through coculturing meniscus cells with synovium-derived stem cells on small intestine submucosa--a pilot study to engineer meniscus tissue constructs.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409