GeneTex
United States (US)

CD105 antibody [MEM-229]

CD105-antibody-MEM-229__GTX78404-1_18121409_876.gif

Cat No. GTX78404

Host Mouse
Clonality Monoclonal
Clone Name MEM-229
Isotype IgG2a
Application WB, ICC/IF, FACS
Reactivity Human, Pig
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

71 kDa kDa. ( Note )

Specificity/Sensitivity

The antibody MEM-229 recognizes human CD105 antigen.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Concentration

1mg/ml

Antigen Species

Human

Immunogen

recombinant vaccinia virus containing human CD105 (L-isoform) cDNA

Purification

Protein A purified

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

P17813, 131195, 2022, END, ENG, ORW, CD105, HHT1, ORW1, FLJ41744

Background

Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex as it binds TGFB1 and TGFB3 with high affinity.Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
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Database

Research Area

DATA IMAGES
CD105-antibody-MEM-229__GTX78404-1_18121409_876.gif

GTX78404 ICC/IF Image

Immunofluorescence staining of an infarcted porcine heart with anti-CD105 (MEM-229; green); cell nuclei stained with DAPI (blue).

Reference