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CD105 antibody [MEM-229]

Anti-CD105 antibody [MEM-229] used in IHC (Frozen sections) (IHC-Fr). GTX78404

Cat No. GTX78404

Host

Mouse

Clonality

Monoclonal

Clone Name

MEM-229

Isotype

IgG2a

Application

WB, ICC/IF, IHC-Fr, FACS

Reactivity

Human, Pig
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Product Note

We do not recommend use of this product for Dog,Horse.

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_625626

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

END , ENG , HHT1 , ORW1 , endoglin , CD105

Cellular Localization

Cell membrane

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-CD105 antibody [MEM-229] used in IHC (Frozen sections) (IHC-Fr). GTX78404

GTX78404 IHC-Fr Image

IHC-Fr analysis of infarcted pig heart tissue using GTX78404 CD105 antibody [MEM-229].
Green : Primary antibody
Blue : DAPI
Diultion : 5μg/ml

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf