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CD105 antibody [N3C3]

Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508
Anti-CD105 antibody [N3C3] used in Western Blot (WB). GTX100508
Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508

Cat. No. GTX100508

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all CD105 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

HUVEC

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the Extracellular domain of human CD105. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1950199

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endoglin , END , HHT1 , ORW1

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508

GTX100508 IHC-P Image

Immunohistochemical analysis of paraffin-embedded SCC15 xenograft, using CD105(GTX100508) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-CD105 antibody [N3C3] used in Western Blot (WB). GTX100508

GTX100508 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with CD105 antibody [N3C3] (GTX100508) diluted at 1:1000.
The observed M.W. is based on the publication: PMID: 10625079

Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508

GTX100508 IHC-P Image

CD105 antibody [N3C3] detects CD105 protein at cell membrane and cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse white adipocyte.
CD105 stained by CD105 antibody [N3C3] (GTX100508) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169