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CD105 antibody [N3C3]

Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508
Anti-CD105 antibody [N3C3] used in Western Blot (WB). GTX100508
Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508

Cat No. GTX100508

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($329),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human CD105. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

endoglin , END , HHT1 , ORW1

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508

GTX100508 IHC-P Image

Immunohistochemical analysis of paraffin-embedded SCC15 xenograft, using CD105(GTX100508) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-CD105 antibody [N3C3] used in Western Blot (WB). GTX100508

GTX100508 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with CD105 antibody [N3C3] (GTX100508) diluted at 1:1000.
The observed M.W. is based on the publication: PMID: 10625079

Anti-CD105 antibody [N3C3] used in IHC (Paraffin sections) (IHC-P). GTX100508

GTX100508 IHC-P Image

CD105 antibody [N3C3] detects CD105 protein at cell membrane and cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse white adipocyte.
CD105 stained by CD105 antibody [N3C3] (GTX100508) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

There are currently no references for CD105 antibody [N3C3] (GTX100508). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD105 antibody [N3C3] (GTX100508). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 329
$ 169