GeneTex
United States (US)

CD11a antibody [MEM-25]

GTX28221_CD11a-antibody-MEM-25__GTX28221-1_19012723_827.jpeg

Cat No. GTX28221

Host Mouse
Clonality Monoclonal
Clone Name MEM-25
Isotype IgG1
Application FACS, IP, Apuri
Reactivity Human
APPLICATION

Application Note

Flow Cytometry, Immunoprecipitation, Functional Applications (blocks binding of LFA-1 complex to ICAM-1. Suitable MAb for affinity purification of LFA-1 from lecocytes).

Calculated MW

129 kDa. ( Note )

Specificity/Sensitivity

a-subunit (CD11a) of human LFA-1.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline pH 7.4 containing 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Leucocytes from a pacient suffering from a LGL-type leukaemia.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Cellular Localization

Cell Membrane and Plasma membrane

Background

CD11a is a glycoprotein with a molecular weight of 26 kDa expressed in combination with the CD18 beta chain. The complex is a member of the beta2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM-2, ICAM-3. CD11a is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T-cells. Anti-CD11a from I21/7 reacts with 97% of thymocytes, 95% of blood lymphocytes, 70% of bone marrow cells of all mouse strains tested.

Database

Research Area

DATA IMAGES
GTX28221_CD11a-antibody-MEM-25__GTX28221-1_19012723_827.jpeg

GTX28221 FACS Image

Surface staining of human peripheral blood cells with anti-human CD11a (MEM-25): PE (GTX78268).

Package List Price ($)
$ 319