Flow Cytometry, Immunoprecipitation, Functional Applications (blocks binding of LFA-1 complex to ICAM-1. Suitable MAb for affinity purification of LFA-1 from lecocytes).
a-subunit (CD11a) of human LFA-1.
Phosphate buffered saline pH 7.4 containing 15mM sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Leucocytes from a pacient suffering from a LGL-type leukaemia.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Cell Membrane and Plasma membrane
CD11a is a glycoprotein with a molecular weight of 26 kDa expressed in combination with the CD18 beta chain. The complex is a member of the beta2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM-2, ICAM-3. CD11a is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T-cells. Anti-CD11a from I21/7 reacts with 97% of thymocytes, 95% of blood lymphocytes, 70% of bone marrow cells of all mouse strains tested.