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CD11a antibody [MEM-83] (Azide Free)

Cat. No. GTX78368

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-83

Isotype

 IgG1

Application

 FACS, IP, Functional Assay, Blocking

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all CD11a products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
IP Assay dependent
Functional Assay Assay dependent
Blocking Assay dependent
Not tested in other applications.

Calculated MW

129 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human peripheral blood lymphocytes

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_625680

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD11A , ITGAL , LFA1 , LFA1A , integrin subunit alpha L , CD11a , LFA-1

Cellular Localization

Cell membrane

Background

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Tran DQ et al. J Immunol 2009; 182 (5) : 2929-38 Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.
Application : Blocking
Reactivity : Mouse
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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations