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CD11b antibody [3V29]

Anti-CD11b antibody [3V29] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX52875

Cat No. GTX52875

Host

Mouse

Clonality

Monoclonal

Clone Name

3V29

Isotype

IgG1

Application

ICC/IF, IHC-Fr, FACS

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-Fr 1:50 - 1:200
FACS 1:500 - 1:2000
Not tested in other applications.

Calculated MW

127 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The immunogen corresponding to a region within amino acids 17 - 1105 of human CD11b.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD11B , CR3A , ITGAM , MAC1 , MAC1A , MO1A , SLEB6 , integrin subunit alpha M , CD11b , Mac-1 , Macrophage 1 antigen

Cellular Localization

Cell membrane,Membrane raft

Background

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-CD11b antibody [3V29] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX52875

GTX52875 ICC/IF Image

ICC/IF analysis of human microglial cells using GTX52875 CD11b antibody [3V29].

REFERENCE

There are currently no references for CD11b antibody [3V29] (GTX52875). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD11b antibody [3V29] (GTX52875). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329