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CD11b antibody [ICRF44] (Low Endotoxin)

Cat No. GTX00481-00

Host

Mouse

Clonality

Monoclonal

Clone Name

ICRF44

Isotype

IgG1

Application

ICC/IF, IHC-Fr, FACS, IP, Functional Assay

Reactivity

Human, Primate
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
Functional Assay Assay dependent
Not tested in other applications.

Calculated MW

127 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2 μm filter sterilized.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rheumatoid synovial cells and human monocytes.

Purification

Protein A purified

Endotoxin

Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD11B,CR3A,ITGAM,MAC1,MAC1A,MO1A,SLEB6,integrin subunit alpha M,CD11b,Mac-1,Macrophage 1 antigen

Cellular Localization

Cell membrane,Membrane raft

Background

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

REFERENCE

There are currently no references for CD11b antibody [ICRF44] (Low Endotoxin) (GTX00481-00). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD11b antibody [ICRF44] (Low Endotoxin) (GTX00481-00). Be the first to share your experience with this product.
Package List Price ($)
$ 319