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United States (US)

CD11b antibody [LT11]

Cat No. GTX10324

Host Mouse
Clonality Monoclonal
Clone Name LT11
Isotype IgG1
Application Immunoassay
Reactivity Human
Package
100 μg ($219)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
Immunoassay Assay dependent
Not tested in other applications.

Calculated MW

127.18 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.1 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Tissue / cell preparation (Human granulocytes)

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Integrin Subunit Alpha M , Cd11B , Cr3A , Mac-1 , Mac1A , Mo1A , Sleb6 , Itgam

Cellular Localization

Cell membrane,Membrane raft

Background

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

REFERENCE
There are currently no references for CD11b antibody [LT11] (GTX10324). Be the first to share your publications with this product.
REVIEW
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Package List Price ($)
$ 219