APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension |
Not tested in other applications.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human granulocytes
Purification
Purified by size-exclusion chromatography
Conjugation
RRID
AB_625617
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD11B , CR3A , ITGAM , MAC1 , MAC1A , MO1A , SLEB6 , integrin subunit alpha M , CD11b , Mac-1 , Macrophage 1 antigen
Cellular Localization
Cell membrane,Membrane raft
Background
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Database
Research Area
DATA IMAGES
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GTX78271 FACS Image
FACS analysis of human peripheral blood using GTX78271 CD11b antibody [MEM-174] (PE).
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REFERENCE
There are currently no references for CD11b antibody [MEM-174] (PE) (GTX78271). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD11b antibody [MEM-174] (PE) (GTX78271). Be the first to share your experience with this product.