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CD11c antibody [5D11]

Anti-CD11c antibody [5D11] used in IHC (Paraffin sections) (IHC-P). GTX01849

Cat. No. GTX01849

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5D11

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($899)
See all CD11c products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

128 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to 258 amino acids from the N-terminus of the external domain of the CD11c molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha X , CD11C , SLEB6

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Database

Research Area

DATA IMAGES

Anti-CD11c antibody [5D11] used in IHC (Paraffin sections) (IHC-P). GTX01849

GTX01849 IHC-P Image

IHC-P analysis of human hairy cell leukemia tissue using GTX01849 CD11c antibody [5D11]. Note the membrane and cytoplasmic staining of malignant cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 899