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CD11c antibody [CBR-p150/4G1] (Azide free)

Cat. No. GTX42471

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CBR-p150/4G1

Isotype

 IgG2a

Application

 IHC-Fr, FACS, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($659)
See all CD11c products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 5-10μg/ml
FACS Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
Mouse anti Human CD11c antibody, clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells.
Not tested in other applications.

Calculated MW

128 kDa. ( Note )

Product Note

This antibody recognizes human CD11c. It does not recognize CD11a, CD11b or CD18.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human CD11c.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha X , CD11C , SLEB6

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 659
Custom Conjugations